Canonical · evidence-anchored

MK-677 evening (recomp support)

Observed protocol pattern: oral MK-677 pre-bed for IGF-1 elevation and lean-mass support during recomp.

12 weeks3 variantsobservational3 evidence nodes
Outcomes this template targets
  • Lean mass preservation
    Weight 100%
  • Body composition improvement
    Weight 80%
  • Lean mass gain
    Weight 85%
  • Muscle retention
    Weight 70%
  • Sleep quality
    Weight 50%
Pick a variant

Same template. Three intensities.

Gentle, Balanced, Advanced. We adjust dose curve, ramp, monitoring and check-in cadence — the science pattern stays identical.

Stack at balanced

Doses adjust with the variant.

  1. 01
    mk-677
    Expect transient water retention and increased appetite — confounds short-term composition reads.
    see variant
    daily, pre-bed
Monitor
  • fasting glucose
  • HbA1c at 12 wk
  • IGF-1 at 8 wk
  • body composition
Stop rules
  • IGF-1 above age-adjusted ULN
  • HbA1c rising into prediabetic range
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Start a journey at the Balanced variant.

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